(-) -Butin
(-) -Butin is a natural flavonoid with potent antioxidant properties. It activates the Nrf2 pathway via PI3K/Akt signaling to upregulate MnSOD, thereby protecting cells from H2O2-induced apoptosis and mitochondrial dysfunction in vitro. This mechanism supports its research in models of oxidative stress-related diseases.
Product Specifications
CAS Number
492-14-8
Product Name Alternative
Butin, Akt, () Butin, () Butin, inhibit, Nrf2, Inhibitor, PI3K
Field of Research
Immunology & Inflammation, Signal Transduction
Purity
98.07% (May vary between batches)
Solubility
DMSO:50 mg/mL (183.65 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (14.69 mM)
Smiles
Oc1ccc2C (=O) C[C@H] (Oc2c1) c1ccc (O) c (O) c1
Molecular Formula
C15H12O5
Molecular Weight
272.25
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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