Caulophyllogenin
Caulophyllogenin, a natural partial PPARγ agonist (EC50 = 12.6 μM) from Kalopanax pictus, suppresses pro-inflammatory cytokine secretion. This activity supports its research utility in studying metabolic and inflammatory conditions, including type-2 diabetes, obesity, and metabolic syndrome, in both cellular and animal models.
Product Specifications
CAS Number
52936-64-8
Product Name Alternative
PPARγ, Segetalic acid, TNF-α, IL Receptor, IL-12, ILReceptor, IL-6, Immunology related, Immunologyrelated, Inflammationrelated, inflammation, Inflammation related, Caulophyllogenin
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Molecular Biology
Purity
98.56% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:100 mg/mL (204.62 mM)
Smiles
C (O) (=O) [C@]12[C@] (C=3[C@@] (C) (C[C@H]1O) [C@@]4 (C) [C@] (CC3) ([C@]5 (C) [C@@] (CC4) ([C@@] (CO) (C) [C@@H] (O) CC5) [H]) [H]) (CC (C) (C) CC2) [H]
Molecular Formula
C30H48O5
Molecular Weight
488.7
Storage Conditions
Store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
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