Eriocalyxin B
Eriocalyxin B is a covalent STAT3 inhibitor that induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma via caspase- and p53-dependent pathways. Its efficacy, demonstrated in vitro, supports its investigation as a candidate therapeutic agent for STAT3-dependent cancers.
Product Specifications
CAS Number
84745-95-9
Product Name Alternative
STAT, cAMP, Apoptosis, inhibit, p65, NFkB, NF-kB, NFκB, Eriocalyxin B, Inhibitor
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.35% (May vary between batches)
Solubility
DMSO:55 mg/mL (159.7 mM)
Smiles
[H][C@@]12C[C@@]3 (C (=O) C1=C) [C@@] ([H]) (CC2) [C@@]12CO[C@]3 (O) [C@@H] (O) [C@]1 ([H]) C (C) (C) C=CC2=O
Molecular Formula
C20H24O5
Molecular Weight
344.4
Storage Conditions
Keep away from direct sunlight, store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
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