Eurycomalactone
Eurycomalactone, a natural compound from Eurycoma longifolia Jack., is a potent NF-κB inhibitor (IC50 = 0.5 μM) . It suppresses protein synthesis and cyclin D1 without affecting TNFα-induced IκBα degradation or IKK/IκBα phosphorylation. This activity makes it a valuable research tool for studying inflammation, cancer, and apoptosis in cellular models.
Product Specifications
CAS Number
23062-24-0
Product Name Alternative
Cyclin D1, DNA double-strand, cisplatin, Antiinfection, Anti-infection, Antifection, inhibit, NF-κB, NFkB, NF-kB, NFκB, Nuclear factor-kappaB, Nuclear factor-κB, Eurycoma longifolia Jack, Eurycomalactone, Inhibitor, protein synthesis
Field of Research
Cell Biology, Infectious Disease & Virology, Signal Transduction
Purity
98.98% (May vary between batches)
Solubility
DMSO:55 mg/mL (157.87 mM)
Smiles
[H][C@]1 (C) [C@@]2 ([H]) OC (=O) [C@]1 ([H]) [C@]1 (C) C (=O) C[C@@]3 ([H]) C (C) =CC (=O) [C@@H] (O) [C@]3 (C) [C@@]1 ([H]) [C@H]2O
Molecular Formula
C19H24O6
Molecular Weight
348.39
Storage Conditions
Keep away from moisture, store at low temperature, keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
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