Garcinone D
Garcinone D is a bioactive small molecule with cytotoxic activity against the CEM-SS cell line (IC50 = 3.2 μg/ml) and inhibits both microsomal aromatase and NF-κB p65 activation (IC50 = 3.2 μM) . This compound is a useful research tool for studying cancer biology and inflammatory pathways in vitro.
Product Specifications
CAS Number
107390-08-9
Product Name Alternative
Inhibitor, Garcinone D, inhibit, Keap1-Nrf2, NF-κB, p65, ReactiveOxygenSpecies, Reactive Oxygen Species, STAT3, STAT
Field of Research
Immunology & Inflammation, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.94% (May vary between batches)
Solubility
DMSO:50 mg/mL (116.69 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.67 mM)
Smiles
COc1c (O) cc2oc3cc (O) c (CC=C (C) C) c (O) c3c (=O) c2c1CCC (C) (C) O
Molecular Formula
C24H28O7
Molecular Weight
428.47
Storage Conditions
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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