Kahweol
Kahweol is a bioactive diterpene with demonstrated anticarcinogenic, anti-angiogenic, and anti-inflammatory properties. It functions by inhibiting NF-κB activation, specifically by blocking IκB degradation and IκB kinase activity, as shown in LPS-stimulated cellular models. This compound is a valuable research tool for studying inflammation and cancer pathways in vitro.
Product Specifications
CAS Number
6894-43-5
Product Name Alternative
Inhibitor, Kahweol, inhibit, NFkB, NFκB, NF-kB, NF-ΚB, IKK, Apoptosis, AMPK, AMP-activated protein kinase, P450
Field of Research
Cell Biology, Epigenetics & Chromatin, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.18 mM) ; DMSO:27.5 mg/mL (87.46 mM)
Smiles
C[C@]12[C@]3 ([C@]4 (C[C@] ([C@] (CO) (O) C4) (CC3) [H]) CC[C@@]1 (C5=C (C=C2) OC=C5) [H]) [H]
Molecular Formula
C20H26O3
Molecular Weight
314.42
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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