Karacoline
Karacolinem is a natural small molecule that inhibits extracellular matrix degradation in intervertebral disc degeneration by targeting the NF-κB signaling pathway. It is a useful research tool for studying IDD mechanisms in both cellular and animal models of disc degeneration.
Product Specifications
CAS Number
39089-30-0
Product Name Alternative
NFkB, NF-κB, NFκB, NF-kB, Karacoline, inhibit, Inhibitor
Field of Research
Signal Transduction
Purity
99.64% (May vary between batches)
Solubility
DMSO:30 mg/mL (79.47 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.3 mM)
Smiles
[H][C@]12C[C@]3 ([H]) [C@] ([H]) ([C@H]1O) [C@] (O) (C[C@@H]2OC) C1C[C@@]2 ([H]) C33C1N (CC) C[C@]2 (C) CC[C@@H]3O
Molecular Formula
C22H35NO4
Molecular Weight
377.52
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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