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Methylnissolin

Methylnissolin, isolated from Astragalus membranaceus, is a bioactive small molecule that inhibits PDGF-BB-induced vascular smooth muscle cell proliferation by blocking the ERK1/2 MAPK pathway. Its mechanism supports research in cardiovascular disease and oncology, with studies indicating antibacterial and anticancer properties in vitro.

Product Specifications

CAS Number

73340-41-7

Product Name Alternative

Astrapterocarpan, 3-Hydroxy-9,10-dimethoxyptercarpan, Inhibitor, Extracellular signal regulated kinases, ERK, Methylnissolin, Platelet-derived growth factor receptor, inhibit, PDGFR

Field of Research

Cardiovascular Research, Signal Transduction

Purity

99.68% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (13.32 mM) ; DMSO:100 mg/mL (332.99 mM)

Smiles

[H][C@@]12COc3cc (O) ccc3[C@]1 ([H]) Oc1c2ccc (OC) c1OC

Molecular Formula

C17H16O5

Molecular Weight

300.31

Storage Conditions

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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