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IXA4

IXA4 is a selective and nontoxic small molecule activator of the IRE1/XBP1s pathway. Its application in research includes the reduction of APP secretion in cellular models and the enhancement of pancreatic function, as evidenced in both in vitro and in vivo studies.

Product Specifications

CAS Number

1185329-96-7

Product Name Alternative

Endoplasmic reticulum (ER) proteostasis, Inhibitor, Inositol requiring enzyme 1, inhibit, IXA 4, IXA4, IXA-4, IRE1, IRE1/XBP1s, protein secretion, unfolded protein response, UPR

Field of Research

Cell Biology

Purity

97.59% (May vary between batches)

Solubility

DMSO:145 mg/mL (332.19 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.58 mM)

Smiles

CN (CCOc1ccc (C) cc1) C (=O) Cn1cc (NC (=O) CCOc2ccccc2) cn1

Molecular Formula

C24H28N4O4

Molecular Weight

436.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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