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Nirmatrelvir

Nirmatrelvir (PF-07321332) is a potent, orally bioavailable inhibitor of the SARS-CoV-2 3CL protease (3CLpro) . It is widely used in both in vitro biochemical assays and in vivo animal models to study antiviral mechanisms and therapeutic potential against COVID-19.

Product Specifications

CAS Number

2628280-40-8

Product Name Alternative

3CLpro, 3CLPRO, Antiviral, Inhibitor, HIV, inhibit, Nirmatrelvir, PF 07321332, PF-07321332, PF07321332, SARS coronavirus, SARSCoV, SARS-CoV, virus

Field of Research

Infectious Disease & Virology

Purity

98.66% (May vary between batches)

Solubility

DMSO:257.5 mg/mL (515.48 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:13 mg/mL (26.02 mM)

Smiles

C (N[C@@H] (C[C@H]1C (=O) NCC1) C#N) (=O) [C@@H]2[C@@]3 ([C@@] (C3 (C) C) (CN2C ([C@@H] (NC (C (F) (F) F) =O) [C@] (C) (C) C) =O) [H]) [H]

Molecular Formula

C23H32F3N5O4

Molecular Weight

499.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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