DCBP-1
DCBP-1 is a small molecule that selectively degrades the p300/CBP proteins by recruiting the CRBN E3 ubiquitin ligase. This targeted degradation has demonstrated potent anti-proliferative effects in multiple myeloma cell lines in vitro, supporting its use as a chemical probe in oncology and epigenetics research.
Product Specifications
CAS Number
2484739-25-3
Product Name Alternative
Cereblon, cell, CBP/p300, CBP, CRBN, degrader, Epigenetic Reader Domain, EpigeneticReaderDomain, dCBP 1, dCBP1, dCBP-1, heterobifunctional, Inhibitor, inhibit, myeloma, MYC, multiple, p300, PROTACs
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Purity
98.21% (May vary between batches)
Solubility
DMSO:50 mg/mL (48.63 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (1.95 mM)
Smiles
C (NC) (=O) N1CC=2C (=NN (C2CC1) C3CCN (C (CCOCCOCCOCCOCCNC=4C=C5C (=CC4) C (=O) N (C5=O) C6C (=O) NC (=O) CC6) =O) CC3) N7C=8C (=CC (=C (C (F) F) C8) C9=CN (C) N=C9) CCC7
Molecular Formula
C51H63F2N11O10
Molecular Weight
1028.11
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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