IU1-248
IU1-248 is a potent and selective small molecule inhibitor of the deubiquitinase USP14, exhibiting an IC50 of 0.83 μM. This compound is a valuable research tool for probing proteasome function and protein homeostasis in cellular and biochemical studies, with applications in neurodegeneration and oncology research.
Product Specifications
CAS Number
2307472-03-1
Product Name Alternative
Deubiquitinase, DUBs, Inhibitor, inhibit, IU1 248, IU1248, IU-1-248, IU1-248, USP14
Field of Research
Cell Biology, Molecular Biology, Protein Biochemistry
Purity
98.49% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (9.78 mM) ; DMSO:80 mg/mL (237.09 mM)
Smiles
Cc1cc (C (=O) CN2CCC (O) CC2) c (C) n1-c1ccc (cc1) C#N
Molecular Formula
C20H23N3O2
Molecular Weight
337.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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