ASK1-IN-2
ASK1-IN-2 is a potent, orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), demonstrating an IC50 of 32.8 nM. It has shown therapeutic potential in preclinical research for ulcerative colitis, with studies investigating its effects in both cellular assays and animal models of inflammatory disease.
Product Specifications
CAS Number
2541792-70-3
Product Name Alternative
Signal-regulating, ulcerative, inhibit, Inhibitor, MAP kinase kinase kinase, MEKK, MAPKKK, MAP3K, colitis, ASK1, ASK1 IN 2, ASK1IN2, ASK-1-IN-2, ASK1-IN-2, Apoptosis
Field of Research
Cell Biology, Signal Transduction
Purity
98.79% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (13.72 mM) ; DMSO:249 mg/mL (683.35 mM)
Smiles
CC (C) n1cnnc1-c1cccc (NC (=O) c2cc3ccc (F) cc3[nH]2) n1
Molecular Formula
C19H17FN6O
Molecular Weight
364.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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