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ASK1-IN-2

ASK1-IN-2 is a potent, orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), demonstrating an IC50 of 32.8 nM. It has shown therapeutic potential in preclinical research for ulcerative colitis, with studies investigating its effects in both cellular assays and animal models of inflammatory disease.

Product Specifications

CAS Number

2541792-70-3

Product Name Alternative

Signal-regulating, ulcerative, inhibit, Inhibitor, MAP kinase kinase kinase, MEKK, MAPKKK, MAP3K, colitis, ASK1, ASK1 IN 2, ASK1IN2, ASK-1-IN-2, ASK1-IN-2, Apoptosis

Field of Research

Cell Biology, Signal Transduction

Purity

98.79% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (13.72 mM) ; DMSO:249 mg/mL (683.35 mM)

Smiles

CC (C) n1cnnc1-c1cccc (NC (=O) c2cc3ccc (F) cc3[nH]2) n1

Molecular Formula

C19H17FN6O

Molecular Weight

364.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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