AZ194
This small molecule inhibitor targets the CRMP2-Ubc9-NaV1.7 complex, disrupting this protein-protein interaction. It is a valuable research tool for studying neuropathic pain mechanisms in both cellular and animal models, as it modulates sodium channel trafficking and neuronal excitability.
Product Specifications
CAS Number
2241651-99-8
Product Name Alternative
Inhibit, Inhibitor, nociceptive neurotransmission, Na+ channels, Na channels, Nav1.7 channel, pain, antinociceptive effects, AZ 194, AZ194, AZ-194, CRMP2-Ubc9 interaction, Sodium Channel, SodiumChannel, sensory neurons
Field of Research
Pharmacology & Drug Discovery
Purity
99.61% (May vary between batches)
Solubility
DMSO:50 mg/mL (88.09 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.52 mM)
Smiles
COc1cc (ccc1OCc1cccc (F) c1) C (=O) N1CCC (CC1) c1nc2ccccc2n1Cc1cccc (F) c1
Molecular Formula
C34H31F2N3O3
Molecular Weight
567.62
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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