FR054
FR054 is a potent small molecule inhibitor targeting PGM3, a key enzyme in the Hexosamine Biosynthetic Pathway (HBP) . It demonstrates significant anti-proliferative and pro-apoptotic effects in breast cancer cell lines, making it a valuable tool for investigating HBP's role in oncology and cancer metabolism research.
Product Specifications
CAS Number
35954-65-5
Product Name Alternative
Cancer, Breast, FR054, FR-054, FR 054, Inhibitor, HBP, Negative, inhibit, TNBC, PGM3, Triple
Field of Research
Metabolism Research
Purity
≥98% (May vary between batches)
Solubility
DMSO:75 mg/mL (227.76 mM) ; H2O:50 mg/mL (151.84 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.07 mM)
Smiles
CC (=O) OC[C@H]1O[C@@H]2OC (C) =N[C@@H]2[C@@H] (OC (C) =O) [C@@H]1OC (C) =O
Molecular Formula
C14H19NO8
Molecular Weight
329.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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