HPK1-IN-7
HPK1-IN-7 is an orally bioavailable, small molecule inhibitor of Hematopoietic Progenitor Kinase 1. It demonstrates selectivity over related kinases IRAK4 (IC50 = 59 nM) and GLK (IC50 = 140 nM) . This compound is a valuable research tool for investigating HPK1 function in immune cell signaling and for preclinical studies in immuno-oncology.
Product Specifications
CAS Number
2320462-65-3
Product Name Alternative
MAP4K, MAPK Kinase Kinase Kinase, MC38, HPK1 IN 7, HPK1IN7, HPK-1-IN-7, HPK1-IN-7, inhibit, Inhibitor, oral, model, PD1, selectivity, tumor
Field of Research
Signal Transduction
Purity
99.31% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.72 mM) ; DMSO:125 mg/mL (272.65 mM)
Smiles
CC1 (C) OC (=O) c2ccc (Nc3ncc (-c4nnco4) c (N[C@H] (CO) c4ccccc4) n3) cc12
Molecular Formula
C24H22N6O4
Molecular Weight
458.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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