CHR-6494 TFA
CHR-6494 TFA is a potent and selective haspin inhibitor (IC50 = 2 nM) that blocks histone H3T3 phosphorylation. It induces apoptosis in various cancer cell lines, such as melanoma and breast cancer, in vitro, supporting its use as a research tool for oncology studies.
Product Specifications
CAS Number
1458630-17-5
Product Name Alternative
Apoptosis, BRAFV600E mutant melanoma cells, cancer cells, CHR 6494, CHR 6494 TFA, CHR6494, CHR-6494, CHR6494 TFA, CHR-6494 TFA, mice, mitotic catastrophe, Inhibitor, NRAS mutant melanoma cells, inhibit, Haspin Kinase
Field of Research
Cell Biology, Immunology & Inflammation
Purity
99.10% (May vary between batches)
Solubility
DMSO:55 mg/mL (135.35 mM)
Smiles
CCCNC1=NN2C (C=C1) =NC=C2C3=CC4=C (NN=C4) C=C3.O=C (O) C (F) (F) F
Molecular Formula
C18H17F3N6O2
Molecular Weight
406.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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