TGFβRI-IN-3
TGFβRI-IN-3 is a potent and highly selective TGFβR1 inhibitor (IC50 = 0.79 nM) with >2000-fold selectivity over MAP4K4. This tool compound is valuable for immuno-oncology research, enabling the study of TGF-β signaling in both cellular assays and in vivo models of cancer and fibrosis.
Product Specifications
CAS Number
2763602-67-9
Product Name Alternative
Smad, TGFβR1, TGFβRI IN 3, TGFβRIIN3, TGFβRI-IN-3, TGFb, TGF-b/Smad, TGFbRI-IN-3, TGFbetaRI-IN-3, TGF-β/Smad, TGFβ, TGF-beta, TGFbeta, TGFbeta/Smad
Field of Research
Stem Cell & Developmental Biology
Purity
98.02% (May vary between batches)
Solubility
DMSO:50 mg/mL (107.4 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.3 mM)
Smiles
N (C=1C2=C (C=C (C=C2) C3=CC=C (S (C) (=O) =O) C=C3) N=CC1) C=4C=C (N=CC4) C5=CC (C) =CC=C5
Molecular Formula
C28H23N3O2S
Molecular Weight
465.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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