MRT-14
MRT-14 is a potent and selective antagonist of Smoothened (Smo), effectively inhibiting the Hedgehog (Hh) signaling pathway. It is a valuable research tool for studying Hh-driven cancers, suitable for both in vitro cellular assays and in vivo preclinical models of malignancies such as medulloblastoma and basal cell carcinoma.
Product Specifications
CAS Number
1263131-83-4
Product Name Alternative
Cancer, Hedgehog, inhibit, Inhibitor, MRT 14, MRT14, MRT-14, Smoothened, Smo
Field of Research
Stem Cell & Developmental Biology
Purity
98.55% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.46 mM) ; DMSO:50 mg/mL (111.49 mM)
Smiles
COc1cc (cc (OC) c1OC) C (=O) NC (=N) Nc1cccc (NC (=O) c2ccccc2) c1
Molecular Formula
C24H24N4O5
Molecular Weight
448.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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