NS3861
NS3861 is a high-affinity agonist selectively targeting heteromeric α3β4 and α4β2 nicotinic acetylcholine receptors, yet it uniquely fails to activate α4-containing subtypes. This functional selectivity, influenced by specific β-subunits and a key serine residue, makes it a valuable research tool for studying nAChR pharmacology and neurobiology in both in vitro and in vivo models.
Product Specifications
CAS Number
216853-59-7
Product Name Alternative
Pharmacology, α4β2 nAChR, α3β4 nAChR, NS3861, NS-3861, NS 3861, Inhibitor, inhibit, Patch Clamp, nAChR, Nicotinic acetylcholine receptors, Heteromeric
Field of Research
Neuroscience
Purity
99.40% (May vary between batches)
Solubility
DMSO:100 mg/mL (351.84 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (14.07 mM)
Smiles
CN1C2CCC1C=C (C2) c1sccc1Br
Molecular Formula
C12H14BrNS
Molecular Weight
284.22
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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