KL-11743
KL-11743 is a small molecule inhibitor that disrupts glucose metabolism, leading to a rapid depletion of NADH and a marked increase in aspartate levels. This action forces a metabolic shift toward mitochondrial oxidative phosphorylation, making it a useful tool for studying cancer metabolism and bioenergetics in both cellular and animal models.
Product Specifications
CAS Number
1369452-53-8
Product Name Alternative
Inhibit, KL11743, KL-11743, KL 11743, Inhibitor, GLUT, GLUT1, GLUT2, GLUT3, GLUT4, glucose, Glucose transporter, transporter
Field of Research
Metabolism Research
Purity
98.12% (May vary between batches)
Solubility
DMSO:14 mg/mL (26.79 mM) ;10% DMSO+90% Corn Oil:2 mg/mL (3.83 mM)
Smiles
CCOc1ccc2nc (nc (Nc3ccc (cc3) -c3cn[nH]c3) c2c1) -c1cccc (OCC (=O) NC (C) C) c1
Molecular Formula
C30H30N6O3
Molecular Weight
522.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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