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KL-11743

KL-11743 is a small molecule inhibitor that disrupts glucose metabolism, leading to a rapid depletion of NADH and a marked increase in aspartate levels. This action forces a metabolic shift toward mitochondrial oxidative phosphorylation, making it a useful tool for studying cancer metabolism and bioenergetics in both cellular and animal models.

Product Specifications

CAS Number

1369452-53-8

Product Name Alternative

Inhibit, KL11743, KL-11743, KL 11743, Inhibitor, GLUT, GLUT1, GLUT2, GLUT3, GLUT4, glucose, Glucose transporter, transporter

Field of Research

Metabolism Research

Purity

98.12% (May vary between batches)

Solubility

DMSO:14 mg/mL (26.79 mM) ;10% DMSO+90% Corn Oil:2 mg/mL (3.83 mM)

Smiles

CCOc1ccc2nc (nc (Nc3ccc (cc3) -c3cn[nH]c3) c2c1) -c1cccc (OCC (=O) NC (C) C) c1

Molecular Formula

C30H30N6O3

Molecular Weight

522.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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