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JI130

JI130 is a small molecule inhibitor that disrupts the transcriptional repressor function of Hes1. This mechanism has demonstrated efficacy in reducing tumor growth in a pancreatic cancer xenograft model, supporting its use in oncology research for studying Notch signaling pathways both in vitro and in vivo.

Product Specifications

CAS Number

2234271-86-2

Product Name Alternative

Hes1, JI 130, JI130, JI-130

Field of Research

Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology

Purity

99.01% (May vary between batches)

Solubility

DMSO:70 mg/mL (185.95 mM)

Smiles

C (=C/C (NCCC1=C (OCC=C) C=CC=C1) =O) \C=2C=3C (=C (OC) C=CC3) NC2

Molecular Formula

C23H24N2O3

Molecular Weight

376.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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