JI130
JI130 is a small molecule inhibitor that disrupts the transcriptional repressor function of Hes1. This mechanism has demonstrated efficacy in reducing tumor growth in a pancreatic cancer xenograft model, supporting its use in oncology research for studying Notch signaling pathways both in vitro and in vivo.
Product Specifications
CAS Number
2234271-86-2
Product Name Alternative
Hes1, JI 130, JI130, JI-130
Field of Research
Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology
Purity
99.01% (May vary between batches)
Solubility
DMSO:70 mg/mL (185.95 mM)
Smiles
C (=C/C (NCCC1=C (OCC=C) C=CC=C1) =O) \C=2C=3C (=C (OC) C=CC3) NC2
Molecular Formula
C23H24N2O3
Molecular Weight
376.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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