PF-04802367
PF-04802367 is a potent and selective dual inhibitor of GSK-3α and GSK-3β, exhibiting low nanomolar IC50 values. Its favorable CNS properties make it a valuable research tool for investigating GSK-3's role in neurological diseases, tauopathies, and mood disorders in both cellular and animal models.
Product Specifications
CAS Number
1962178-27-3
Product Name Alternative
Tau, synthase, protein, PF367, PF-367, PF04802367, PF-04802367, PF 367, PF 04802367, phosphorylation, Alzheimer, disease, inhibit, kinase-3, neurodegenerative, neurology, Inhibitor, Glycogen synthase kinase-3, Glycogen, Glycogen synthase kinase 3, GSK3, GSK-3, GSK-3α/β
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Purity
98.76% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.06 mM) ; DMSO:100 mg/mL (276.41 mM)
Smiles
COc1ccc (cc1Cl) -c1ocnc1C (=O) NCCCn1cncn1
Molecular Formula
C16H16ClN5O3
Molecular Weight
361.78
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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