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PF-04802367

PF-04802367 is a potent and selective dual inhibitor of GSK-3α and GSK-3β, exhibiting low nanomolar IC50 values. Its favorable CNS properties make it a valuable research tool for investigating GSK-3's role in neurological diseases, tauopathies, and mood disorders in both cellular and animal models.

Product Specifications

CAS Number

1962178-27-3

Product Name Alternative

Tau, synthase, protein, PF367, PF-367, PF04802367, PF-04802367, PF 367, PF 04802367, phosphorylation, Alzheimer, disease, inhibit, kinase-3, neurodegenerative, neurology, Inhibitor, Glycogen synthase kinase-3, Glycogen, Glycogen synthase kinase 3, GSK3, GSK-3, GSK-3α/β

Field of Research

Signal Transduction, Stem Cell & Developmental Biology

Purity

98.76% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.06 mM) ; DMSO:100 mg/mL (276.41 mM)

Smiles

COc1ccc (cc1Cl) -c1ocnc1C (=O) NCCCn1cncn1

Molecular Formula

C16H16ClN5O3

Molecular Weight

361.78

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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