HeE1-2Tyr
HeE1-2Tyr is a pyridobenzothiazole-based small molecule inhibitor targeting flavivirus RNA-dependent RNA polymerase (RdRp) . It demonstrates in vitro inhibitory activity against West Nile, Dengue, and SARS-CoV-2 RdRps with an IC50 of 27.6 μM. This compound is a useful research tool for antiviral studies targeting viral replication mechanisms.
Product Specifications
CAS Number
2245195-67-7
Product Name Alternative
SARSCoV, SARS-CoV, SARS coronavirus, SARS-CoV-2, West, RdRp, inhibit, Nile, flavivirus, Inhibitor, HeE1 2Tyr, HeE12Tyr, HeE-1-2Tyr, HeE1-2Tyr, Dengue
Field of Research
Infectious Disease & Virology
Purity
95.86% (May vary between batches)
Solubility
DMSO:100 mg/mL (171.62 mM)
Smiles
OC (=O) [C@H] (Cc1ccc (O) cc1) NC (=O) c1cc (-c2ccccc2) c (=O) n2c3cc (OC4CCCCC4) ccc3sc12
Molecular Formula
C33H30N2O6S
Molecular Weight
582.67
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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