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PHD-1-IN-1

PHD-1-IN-1 is a highly potent and selective inhibitor of the HIF prolyl hydroxylase domain 1 (PHD1) enzyme, demonstrating an IC50 of 34 nM. This compound is a valuable chemical tool for investigating hypoxia signaling pathways and has been utilized in both cellular and animal models to study ischemic and inflammatory conditions.

Product Specifications

CAS Number

2009343-14-8

Product Name Alternative

Active, Arg367-out, Inhibitor, HIF, HIF ProlylHydroxylase, HIF/HIF ProlylHydroxylase, HIF Prolyl-Hydroxylase, HIF/HIF Prolyl-Hydroxylase, HIF/HIFProlylHydroxylase, HIFProlylHydroxylase, HIF-PH, HIFs, Hypoxia-inducible factors, Fe2+, inhibit, ion, iron, pocket, orally, PHD 1 IN 1, PHD1, PHD-1, PHD1IN1, PHD-1-IN-1, site

Field of Research

Epigenetics & Chromatin, Metabolism Research

Purity

99.74% (May vary between batches)

Solubility

DMSO:11 mg/mL (49.95 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:8 mg/mL (36.33 mM)

Smiles

N#Cc1ccc (cc1) -c1cccc2ncnn12

Molecular Formula

C13H8N4

Molecular Weight

220.23

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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