Cedirogant
Cedirogant (ABBV-157) is an orally bioavailable, small molecule inverse agonist of the retinoid-related orphan receptor γt (RORγt) . It is utilized in preclinical and clinical research for autoimmune conditions like psoriasis, investigating its mechanism and efficacy in modulating IL-17-driven inflammatory pathways.
Product Specifications
CAS Number
2055496-11-0
Product Name Alternative
Inhibit, Inhibitor, inverse, Cedirogant, agonist, ABBV157, ABBV-157, ABBV 157, RAR-related orphan receptor, RORγt, ROR, psoriasis
Field of Research
Metabolism Research
Purity
99.20% (May vary between batches)
Solubility
DMSO:200 mg/mL (365.11 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (9.13 mM)
Smiles
OC (=O) CC1CCN (CC1) C (=O) c1ccc (Cl) c (Cn2ccc3cc (cc (Cl) c23) C (F) (F) F) c1Cl
Molecular Formula
C24H20Cl3F3N2O3
Molecular Weight
547.78
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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