Dalpiciclib
Dalpiciclib (SHR-6390) is a potent and selective oral inhibitor of CDK4/6, exhibiting antitumor activity in models such as esophageal squamous cell carcinoma. It functions by inhibiting Rb phosphorylation, inducing G1 arrest, and has demonstrated efficacy in both in vitro and in vivo studies across various cancer research fields.
Product Specifications
CAS Number
1637781-04-4
Product Name Alternative
CDK, CDK4, CDK6, Cyclin dependent kinase, Dalpiciclib, Eca 109, Eca 9706, and KYSE-510 ESCC, antitumor activity, BT-474/T, inhibit, MCF7, MCF7/TR, Inhibitor, SHR6390, SHR-6390, SHR 6390
Field of Research
Cell Biology
Purity
98.32% (May vary between batches)
Solubility
DMSO:< 1 mg/mL (insoluble)
Smiles
O=C1N (C=2C (C (C) =C1C (C) =O) =CN=C (NC3=CC=C (C=N3) C4CCNCC4) N2) C5CCCC5
Molecular Formula
C25H30N6O2
Molecular Weight
446.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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