3′,4′,7-Trihydroxyflavone
7,3',4'-Trihydroxyflavone is a bioactive flavonoid that suppresses osteoclast formation by targeting NFATc1. It potently inhibits RANKL-induced osteoclast differentiation from bone marrow macrophages (BMMs) in vitro, making it a useful research tool for studying bone resorption and osteoporosis-related pathways.
Product Specifications
CAS Number
2150-11-0
Product Name Alternative
RANKL, broad bean pods, ATPase, 3′,4′,7 Trihydroxyflavone , 3′,4′,7-Trihydroxyflavone, 3′,4′,7Trihydroxyflavone , p38MAPK, p38 MAPK, NF-κB, Nuclear factor of activated Tcells (NFAT), NFkB, NFκB, NF-kB, inhibit, Inhibitor, flavonoid aglycon
Field of Research
Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.61% (May vary between batches)
Solubility
DMSO:55 mg/mL (203.52 mM)
Smiles
Oc1ccc2c (c1) oc (cc2=O) -c1ccc (O) c (O) c1
Molecular Formula
C15H10O5
Molecular Weight
270.24
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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