Dolastatin 10
Dolastatin 10 is a potent antimitotic peptide that acts by inhibiting tubulin polymerization. Its mechanism has been extensively studied in vitro and it has served as a lead compound for the development of novel anticancer agents evaluated in preclinical in vivo models.
Product Specifications
CAS Number
110417-88-4
Product Name Alternative
DLS 10, DLS10, DLS-10, Dolastatin 10, Dolastatin10, Dolastatin-10, ADCCytotoxin, ADC Cytotoxin, ADC Payload, inhibit, NSC 376128, Microtubule/Tubulin, MicrotubuleAssociated, Microtubule Associated, NSC376128, NSC-376128, Inhibitor
Field of Research
Signal Transduction
Purity
99.00% (May vary between batches)
Solubility
DMSO:100 mg/mL (127.37 mM)
Smiles
CC[C@H] (C) [C@@H] ([C@@H] (CC (=O) N1CCC[C@H]1[C@H] (OC) [C@@H] (C) C (=O) N[C@@H] (Cc1ccccc1) c1nccs1) OC) N (C) C (=O) [C@@H] (NC (=O) [C@H] (C (C) C) N (C) C) C (C) C
Molecular Formula
C42H68N6O6S
Molecular Weight
785.09
Storage Conditions
Keep away from moisture | Powder: -20°C for 3 years | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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