Ko 143
Ko 143 is a potent and selective small molecule inhibitor of the ABCG2/BCRP transporter. This compound is widely used in pharmacological research to study drug efflux, bioavailability, and multidrug resistance in both cellular and animal models.
Product Specifications
CAS Number
461054-93-3
Product Name Alternative
Breast cancer resistance protein, BCRP, ABCG2, Ko 143, Ko143, Ko-143, inhibit, Inhibitor
Field of Research
Pharmacology & Drug Discovery
Purity
98.91% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.03 mM) ; DMSO:90 mg/mL (191.66 mM) ; H2O:Insoluble
Smiles
COc1ccc2c3C[C@@H]4N ([C@@H] (CC (C) C) c3[nH]c2c1) C (=O) [C@H] (CCC (=O) OC (C) (C) C) NC4=O
Molecular Formula
C26H35N3O5
Molecular Weight
469.57
Storage Conditions
Store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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