SR-3677
SR-3677 is a potent and selective ROCK2 inhibitor with an IC50 of 3 nM. This compound is a valuable research tool for investigating Rho-kinase signaling in cellular assays and has been utilized in preclinical studies exploring fibrosis, hypertension, and neurological disorders.
Product Specifications
CAS Number
1072959-67-1
Product Name Alternative
Autophagy, Inhibitor, inhibit, ROK, ROCK, ROCK1, ROCK2, Rho-associated kinase, Rho-associated protein kinase, Rho-kinase, SR 3677, SR3677, SR-3677
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.46% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.9 mM) ; DMSO:40 mg/mL (97.93 mM)
Smiles
CN (C) CCOc1cc (ccc1NC (=O) C1COc2ccccc2O1) -c1cn[nH]c1
Molecular Formula
C22H24N4O4
Molecular Weight
408.45
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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