Cucurbitacin I
Cucurbitacin I (JSI-124) is a natural product that selectively inhibits the JAK2/STAT3 signaling pathway. It has demonstrated anti-cancer activity in both in vitro cell-based assays and in vivo animal models, making it a valuable research tool for oncology and signal transduction studies.
Product Specifications
CAS Number
2222-07-3
Product Name Alternative
Cucurbitacin I, Elatericin B, inhibit, JSI 124, JSI124, JSI-124, Inhibitor, NSC 521777, Janus kinase, JAK, JAK2, NSC521777, NSC-521777, STAT, STAT3
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
96.69% (May vary between batches)
Solubility
DMSO:95 mg/mL (184.59 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (4.86 mM)
Smiles
[H][C@@]12CC=C3[C@@] ([H]) (C=C (O) C (=O) C3 (C) C) [C@]1 (C) C (=O) C[C@]1 (C) [C@H] ([C@H] (O) C[C@@]21C) [C@@] (C) (O) C (=O) \C=C\C (C) (C) O
Molecular Formula
C30H42O7
Molecular Weight
514.65
Storage Conditions
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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