What is the catalog number for Phorbol 12-myristate 13-acetate?

The catalog number for Phorbol 12-myristate 13-acetate is orb1296136.

What sizes are available for Phorbol 12-myristate 13-acetate?

Phorbol 12-myristate 13-acetate is available in the following size(s): 1 mg, 5 mg.

How many pack sizes does Phorbol 12-myristate 13-acetate come in?

Phorbol 12-myristate 13-acetate is available in 2 different pack sizes.

Is Phorbol 12-myristate 13-acetate in stock?

Phorbol 12-myristate 13-acetate is currently made to order / not held in immediate stock. Contact us for lead time.

Phorbol 12-myristate 13-acetate

Phorbol 12-myristate 13-acetate (PMA) is a potent cell-permeable activator of protein kinase C (PKC), sphingosine kinase (SphK), and the NF-κB pathway. It is widely utilized in research to differentiate monocytic THP-1 cells into macrophages in vitro and to establish inflammatory models, such as dermatitis, in vivo.

Product Specifications

CAS Number

16561-29-8

Product Name Alternative

Protein kinase C, S1PReceptor, S1P Receptor, TPA, SphK, Sphingosine kinase, PKC, Phorbol 12 myristate 13 acetate, Phorbol 12-myristate, Phorbol 12myristate 13acetate, Phorbol 12-myristate 13-acetate, Phorbol myristate, Nuclear factor-kappaB, Nuclear factor-κB, PMA, NFκB, NF-κB, NFkB, NF-kB, Inhibitor, inhibit

Field of Research

Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction

Purity

98.55% (May vary between batches)

Solubility

DMSO: 60 mg/mL (97.27 mM), Sonication is recommended. H2O: Insoluble

Smiles

[H][C@]12[C@]3 ([H]) C=C (CO) C[C@]4 (O) C (=O) C (C) =C[C@@]4 ([H]) [C@@]3 (O) [C@H] (C) [C@@H] (OC (=O) CCCCCCCCCCCCC) [C@@]1 (OC (C) =O) C2 (C) C

Molecular Formula

C36H56O8

Molecular Weight

616.83

Storage Conditions

Keep away from direct sunlight, store under nitrogen, store at low temperature, keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.