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SAH

S-Adenosylhomocysteine (SAH) is an amino acid derivative and metabolic intermediate that potently inhibits the METTL3-METTL14 methyltransferase complex (IC50=0.9 μM) . It serves as a key regulator in methylation-dependent pathways and is widely used in epigenetic research, including studies on RNA modification and cellular metabolism in vitro.

Product Specifications

CAS Number

979-92-0

Product Name Alternative

Endogenous Metabolite, Inhibitor, EndogenousMetabolite, inhibit, S-Adenosylhomocysteine, SAH, SAH (S-Adenosylhomocysteine)

Field of Research

Metabolism Research

Purity

98.01% (May vary between batches)

Solubility

DMSO:63.1 mg/mL (164.15 mM) ;10% DMSO+90% Saline:12.5 mg/mL (32.52 mM)

Smiles

N[C@@H] (CCSC[C@H]1O[C@H] ([C@H] (O) [C@@H]1O) n1cnc2c (N) ncnc12) C (O) =O

Molecular Formula

C14H20N6O5S

Molecular Weight

384.41

Storage Conditions

Store under nitrogen, store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

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