ETP-46321
ETP-46321 is a potent, orally active small molecule inhibitor targeting PI3Kα and PI3Kδ isoforms with Kis of 2.3 nM and 14.2 nM, respectively. It is a valuable research tool for investigating PI3K signaling in oncology and immunology, supporting both in vitro cellular assays and in vivo pharmacokinetic and efficacy studies.
Product Specifications
CAS Number
1252594-99-2
Product Name Alternative
ETP 46321, ETP46321, ETP-46321, Inhibitor, inhibit, p110δ, p110γ, p110β, p110α, Phosphoinositide 3-kinase, PI3K, PI3Kα, PI3Kα-E545K, PI3Kα-H1047R, PI3Kα-E542K, PI3Kδ
Field of Research
Signal Transduction
Purity
99.47% (May vary between batches)
Solubility
DMSO:30 mg/mL (63.35 mM)
Smiles
CS (=O) (=O) N1CCN (Cc2cn3cc (nc (N4CCOCC4) c3n2) -c2cnc (N) nc2) CC1
Molecular Formula
C20H27N9O3S
Molecular Weight
473.55
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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