NVP-CGM097
NVP-CGM097 (CGM097) is a potent and selective small-molecule inhibitor of the MDM2-p53 interaction, exhibiting an IC50 of 1.7 nM against human MDM2. It is widely used in cancer research to reactivate p53 pathways, facilitating studies on tumor suppression in both cellular and animal models.
Product Specifications
CAS Number
1313363-54-0
Product Name Alternative
Field of Research
Cell Biology, Protein Biochemistry
Purity
98.77% (May vary between batches)
Solubility
DMSO:48 mg/mL (72.81 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.03 mM) ; H2O:Insoluble
Smiles
COc1cc2CC (=O) N ([C@@H] (c3ccc (Cl) cc3) c2cc1OC (C) C) c1ccc (cc1) N (C) C[C@H]1CC[C@@H] (CC1) N1CCN (C) C (=O) C1
Molecular Formula
C38H47ClN4O4
Molecular Weight
659.26
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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