UNC0646
UNC0646 is a potent, selective dual inhibitor of the histone methyltransferases G9a and GLP, demonstrating nanomolar cellular activity and low cytotoxicity. It is a valuable chemical probe for epigenetic research, widely used in vitro and in vivo to study histone methylation's role in cancer, neurology, and development.
Product Specifications
CAS Number
1320288-17-2
Product Name Alternative
SAR, PKMT, UNC 0646, UNC0646, UNC-0646, p53, KMT1D, inhibit, HistoneMethyltransferase, Histone Methyltransferase, Inhibitor, H3K9me2, G9a, GLP, EHMT1, cell-penetration, chromatin
Field of Research
Epigenetics & Chromatin
Purity
99.59% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (6.43 mM) ; DMSO:30 mg/mL (48.24 mM)
Smiles
COc1cc2c (NC3CCN (CC3) C3CCCCC3) nc (nc2cc1OCCCN1CCCCC1) N1CCCN (CC1) C (C) C
Molecular Formula
C36H59N7O2
Molecular Weight
621.9
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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