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AC710

AC710 is a potent small molecule inhibitor targeting PDGFRs, with high affinity for FLT3, KIT, CSF1R, PDGFRα, and PDGFRβ (Kd values 0.6-1.57 nM) . It is a valuable research tool for studying receptor tyrosine kinase signaling in oncology and hematology research, applicable in both cellular and animal models.

Product Specifications

CAS Number

1351522-04-7

Product Name Alternative

CD135, Cluster of differentiation antigen 135, CD117, cKit, c-Kit, AC710, AC-710, AC 710, FLT3, Fms like tyrosine kinase 3, Inhibitor, inhibit, Kit, Platelet-derived growth factor receptor, PDGFR, PDGFRβ, PDGFRα, SCFR

Field of Research

Cardiovascular Research, Signal Transduction

Purity

99.48% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween-80+45% Saline:0.5 mg/mL (0.89 mM) ; DMSO:15 mg/mL (26.66 mM)

Smiles

CCN1C (C) (C) CC (CC1 (C) C) Oc1ccc (nc1) C (=O) Nc1ccc (NC (=O) Nc2cc (on2) C (C) (C) C) cc1

Molecular Formula

C31H42N6O4

Molecular Weight

562.7

Storage Conditions

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

Available Sizes

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