CWHM-12
CWHM-12 is a highly potent small molecule inhibitor targeting αV integrins, with sub-nanomolar IC50 values against αvβ8, αvβ3, αvβ6, and αvβ1. This compound is a valuable research tool for studying integrin-mediated pathways in fibrosis, cancer, and angiogenesis, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1564286-55-0
Product Name Alternative
CWHM 12, CWHM12, CWHM-12, inhibit, Inhibitor, Integrin, αVβ3 integrin, αVβ6 integrin, αVβ8 integrin, αVβ1 integrin
Field of Research
Signal Transduction
Purity
98.05% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.39 mM) ; DMSO:45 mg/mL (76.21 mM)
Smiles
CC (C) (C) c1cc (Br) cc (c1) [C@H] (CC (O) =O) NC (=O) CNC (=O) c1cc (O) cc (NC2=NCC (O) CN2) c1
Molecular Formula
C26H32BrN5O6
Molecular Weight
590.47
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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