BAR502
BAR502 is a dual agonist targeting both the GPBAR1 (TGR5) and FXR receptors, with respective IC50 values of 0.4 μM and 2 μM. This small molecule is a valuable research tool for investigating metabolic and inflammatory pathways in both in vitro and in vivo models of liver and intestinal diseases.
Product Specifications
CAS Number
1612191-86-2
Product Name Alternative
BAR 502, BAR502, BAR-502, Autophagy, G-protein coupled receptor 19, GPBAR1, GPCR19, FXR, G protein-coupled Bile Acid Receptor 1, Inhibitor, NR1H4, inhibit, TGR5
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery
Purity
99.91% (May vary between batches)
Solubility
DMF:48 mg/mL (122.26 mM)
Smiles
CC[C@H]1[C@@H] (O) [C@H]2[C@@H]3CC[C@H] ([C@H] (C) CCO) [C@@]3 (C) CC[C@@H]2[C@@]2 (C) CC[C@@H] (O) C[C@@H]12
Molecular Formula
C25H44O3
Molecular Weight
392.62
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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