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PLX51107

PLX51107 is a potent, selective BET bromodomain inhibitor with low nanomolar affinity for BRD2, BRD3, BRD4, and BRDT. This small molecule is a valuable research tool for investigating BET protein function in oncology, immunology, and inflammation, supporting both in vitro biochemical assays and in vivo preclinical studies.

Product Specifications

CAS Number

1627929-55-8

Product Name Alternative

BET, inhibit, PLX 51107, PLX51107, PLX-51107, Inhibitor, EpigeneticReaderDomain, Epigenetic Reader Domain

Field of Research

Epigenetics & Chromatin

Purity

99.75% (May vary between batches)

Solubility

DMSO:70 mg/mL (159.64 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.56 mM)

Smiles

C[C@@H] (c1ccccn1) n1cc (-c2ccc (cc2) C (O) =O) c2ncc (cc12) -c1c (C) noc1C

Molecular Formula

C26H22N4O3

Molecular Weight

438.48

Storage Conditions

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

Available Sizes

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