Olafertinib
Olafertinib (RX-518) is an oral, irreversible, and mutant-selective EGFR inhibitor designed to target T790M-mediated resistance in non-small cell lung cancer (NSCLC) . It demonstrates potent activity in both cellular assays and in vivo xenograft models, supporting its investigation as a therapeutic agent for EGFR-mutant NSCLC.
Product Specifications
CAS Number
1660963-42-7
Product Name Alternative
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.43% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.54 mM) ; DMSO:120 mg/mL (226.17 mM) ; H2O:Insoluble
Smiles
OCCN1CCN (CC1) c1ccc (Nc2ncc3cccc (-c4cccc (NC (=O) C=C) c4) c3n2) c (F) c1F
Molecular Formula
C29H28F2N6O2
Molecular Weight
530.57
Storage Conditions
Store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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