MK-0557
MK-0557 is a potent, selective, and orally bioavailable neuropeptide Y5 receptor antagonist with a Ki of 1.6 nM. This compound is a valuable research tool for investigating the role of the Y5 receptor in appetite regulation and energy homeostasis, supporting both in vitro binding studies and in vivo pharmacological research.
Product Specifications
CAS Number
328232-95-7
Product Name Alternative
NPY receptor, inhibit, MK 0557, MK0557, MK-0557, NeuropeptideYReceptor, Neuropeptide Y Receptor, neuropeptide Y (NPY) Y5 receptor, neuropeptide Y (NPY) receptor, Inhibitor, Y5 receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.81% (May vary between batches)
Solubility
DMSO:25 mg/mL (61.51 mM) ;10% DMSO+90% Corn Oil:2 mg/mL (4.92 mM)
Smiles
Fc1ccccc1-n1ccc (NC (=O) [C@H]2CC[C@]3 (CC2) OC (=O) c2ccncc32) n1
Molecular Formula
C22H19FN4O3
Molecular Weight
406.41
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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