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LY450108

LY450108 is a positive allosteric modulator of the AMPA receptor. This compound serves as a research tool for investigating synaptic plasticity and has been utilized in both in vitro and in vivo models relevant to Parkinson's disease research.

Product Specifications

CAS Number

376594-67-1

Product Name Alternative

Inhibit, Ionotropic glutamate receptors, Inhibitor, Parkinson's, LY450108, LY-450108, LY 450108, iGluR, AMPAR, AMPA, depression

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

98.80% (May vary between batches)

Solubility

H2O:1 mg/mL (2.52 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.04 mM) ; DMSO:50 mg/mL (126.12 mM)

Smiles

CC (C) S (=O) (=O) NC[C@H] (C) c1ccc (NC (=O) c2cc (F) cc (F) c2) cc1

Molecular Formula

C19H22F2N2O3S

Molecular Weight

396.45

Storage Conditions

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

Available Sizes

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