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Cenicriviroc

Cenicriviroc (TAK-652) is an orally bioavailable dual CCR2 and CCR5 antagonist. It exhibits anti-HIV-1/2 activity and has been investigated in research for its anti-inflammatory effects in models of liver and kidney fibrosis, both in vitro and in vivo.

Product Specifications

CAS Number

497223-25-3

Product Name Alternative

Inhibit, HIV, HIV Protease, HIVProtease, HIV-2, HIV-1, Inhibitor, Human immunodeficiency virus, CCR2, CCR, Cenicriviroc, CCR5, CC chemokine receptor, TAK 652, TAK652, TAK-652, TBR 652, TBR652, TBR-652

Field of Research

Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Purity

97.87% (May vary between batches)

Solubility

DMSO:120 mg/mL (172.18 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (5.74 mM)

Smiles

CC (C) CN1CCC/C (C (NC2=CC=C ([S@] (CC3=CN=CN3CCC) =O) C=C2) =O) =C\C4=CC (C5=CC=C (OCCOCCCC) C=C5) =CC=C41

Molecular Formula

C41H52N4O4S

Molecular Weight

696.94

Storage Conditions

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

Available Sizes

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