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SAR-100842

SAR-100842 (SAR100842) is a potent, selective, orally available antagonist of the Lysophosphatidic Acid 1 Receptor (LPA1 receptor) with IC50 of 31 nM in β-arrestin assays; demonstrates potential for the treatment of systemic sclerosis and related fibrotic diseases.Other Indication Phase 2 Discontinued.

Product Specifications

CAS Number

1195941-38-8

Product Name Alternative

SAR100842

Purity

>98% (HPLC)

Solubility

DMSO: Soluble (< 1 mg/ml refers to the product slightly soluble or insoluble)

Smiles

O=C (C1 (NC (C2=CC=C (OC) C (OCCC3=CC=CC (C) =C3) =C2) =O) CC4=C (C=CC=C4) C1) O

Molecular Formula

C27H27NO5

Molecular Weight

445.515

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

2-{4-methoxy-3-[2- (3-methylphenyl) ethoxy]benzamido}-2,3-dihydro-1H-indene-2-carboxylic acid

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